Overexpression of miR-126 Protects Hypoxic-Reoxygenation-Exposed HUVEC Cellular Injury through Regulating LRP6 Expression

Table 1

Clinical data of the study population.

Variables	Healthy volunteers (55)	Stable CAD group (153)	Unstable CAD group (70)
Age (years)				0.186	0.157	0.319
Male/female	30/25	85/68	43/27	0.122	0.504	0.183
Current smoker	59% (32)	72% (110)	75% (52)	0.708	0.643	1.00
Essential hypertension	—	74% (113)	82% (57)	—	—	0.068
Hyperlipidemia	—	85% (130)	89% (62)	—	—	0.274
Family history	9% (5)	63% (96)	66% (46)	0.000	0.000	0.832
Diabetes mellitus	—	26% (40)	32% (22)	—	—	0.159
SBP (mmHg)				0.085	0.066	0.114
DBP (mmHg)				0.094	0.081	0.132
Heart rate (beats/min)				0.407	0.375	0.729
Fasting glucose (mmol/L)				0.073	0.069	0.251
Cr (μmol/L)				0.073	0.069	0.148
hs-CRP (mg/L)				0.000	0.000	0.091
Total cholesterol				0.084	0.075	0.116
HDL-C (mmol/L)				0.095	0.087	0.123
Triglyceride (mmol/L)				0.099	0.095	0.104
LDL-C (mmol/L)				0.219	0.157	0.289
Left ventricular ejection fraction (%)				0.326	0.271	0.467
AST (U/L)				0.794	0.592	0.813
ALT (U/L)				0.203	0.177	0.369

CAD: coronary artery disease patients; SBP: systolic blood pressure; DBP: diastolic blood pressure; AST: aspartate aminotransferase; ALT: alanine aminotransferase; : healthy participants and stable CAD; : health control subject versus unstable CAD; : stable CAD versus unstable CAD patients.