Dietary Fatty Acid Regulation of the NLRP3 Inflammasome via the TLR4/NF-κB Signaling Pathway Affects Chondrocyte Pyroptosis

Figure 2

Effects of dietary FAs on articular cartilage in mice. (a) H&E staining (200x;  μm). The arrows represented local aggregation or absence of cartilages. (b) Safranin O staining (100x;  μm). The arrows indicated cartilage thinning or loss. (c) Safranin O/Fast Green staining (100x;  μm). The arrows indicated the fuzzy fracture of the tide line. (d) Modified Mankin scores and OARSI scores. (e) Histogram of footprints of mice in each group from DMM hind limbs. (f) The bar graph data of print area (cm²), max contact (%), duty cycle (%), and swing speed (cm/s). The data are presented as the , . and versus the LD group; ^# and ^## versus the sham group; ^ and ^^ versus the SFA group; ^& and ^&& versus the MUFA group; ^$ and ^$$ versus the n-6 group.

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