TREM-1 Modulates Dendritic Cells Maturation and Dendritic Cell-Mediated T-Cell Activation Induced by ox-LDL

Figure 1

ox-LDL-induced DCs TREM-1 expression. (a) DCs at day 6 were treated with LDL or ox-LDL at different time (0, 6, 12, and 24 h) or at different concentration (25, 50, or 100 μg mL⁻¹) for 24 h. Then, the protein levels of TREM-1 were determined. (b) DCs at day 6 were treated with LDL or ox-LDL at 50 μg mL⁻¹ at 0, 6, 12, and 24 h, and then the mRNA levels of TREM-1 were determined. (c) DCs at day 6 were treated with ox-LDL at 25, 50, or 100 μg mL⁻¹ for 24 h, and then the mRNA levels of TREM-1 were determined. , compared with control cells; , compared with ox-LDL-treated cells.

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