A Comparison of the Antiosteoporotic Effects of Cornelian Cherry (Cornus mas L.) Extracts from Red and Yellow Fruits Containing Different Constituents of Polyphenols and Iridoids in Osteoblasts and Osteoclasts

Figure 4

The effects of the Cornus mas L. extracts on the expression changes of osteoblast-specific genes in the primary osteoblasts of mice. The primary osteoblasts were incubated with ascorbic acid (50 μg/mL) and β-glycerophosphate (10 mM) with or without 10 μg/mL of Cornus mas L. extracts for 3 days. Osteoblast-specific genes including Alpl and Runx2 were measured by qRT-PCR using gene-specific primers. CM, Cornus mas L. extract treatment. vs. induction (Student’s -test).