A Comparison of the Antiosteoporotic Effects of Cornelian Cherry (Cornus mas L.) Extracts from Red and Yellow Fruits Containing Different Constituents of Polyphenols and Iridoids in Osteoblasts and Osteoclasts

Figure 5

The effect of Cornus mas L. extracts on the cellular viability of primary osteoclasts in mice. The primary monocytes were incubated with macrophage colony-stimulating factor (M-CSF) (50 ng/mL) and receptor activator of nuclear factor-kappa B ligand (RANKL) (50 ng/mL) and cotreated with RED EXT1 (a), YL EXT2 (b), and YL EXT3 (c) at three different concentrations (2, 5, and 10 μg/mL) for 5 days. Cell viability was assessed using a WST assay. CM, Cornus mas L. extract.

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(b)

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