Chitosan Oligosaccharides Alleviate H₂O₂-stimulated Granulosa Cell Damage via HIF-1α Signaling Pathway

Figure 5

COS improved mitochondrial function in H₂O₂-stimulated KGN cells. (a) MitoTracker was stained on KGN by immunofluorescence. (b) The statistics histogram of immunofluorescence expressed fluorescent intensity. (c) JC-1 red, JC-1 green, and merge images. (d) Statistics data were expressed in terms of the ratio of JC-1 red to JC-1 green. Data are presented as the (). , , or vs. the control group; ^#, ^##, or ^### vs. the H₂O₂ group. Scale bar: (a): 100 μm; (c): 50 μm.

(a)

(b)

(c)

(d)