Research Article

Chitosan Oligosaccharides Alleviate H2O2-stimulated Granulosa Cell Damage via HIF-1α Signaling Pathway

Figure 7

The effect of the COS treatment on the HIF-1α/VEGF pathway in H2O2-stimulated KGN cells. (a) The levels of TGF-β1, 4-HNE, and 8-OHdG. (b) The statistics histogram of western blotting are expressed as band density normalized versus actin. (c) Cell apoptosis rates. (d) Quantitative results of KGN cell apoptosis rate. (e, f) Cellular GSH content and cell viability. Data are presented as the (). , , or vs. the control group; #, ##, or ### vs. the H2O2 group; &, &&, or &&& vs. the H2O2+100 COS+KC7F2 group.
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