Investigating the Mechanisms of Jieduquyuziyin Prescription Improves Lupus Nephritis and Fibrosis via FXR in MRL/lpr Mice

<div>Ingenuity pathway analysis and GEO database combined to analyze serum differential metabolite-related pathways and targets. IPA software was used to analyze the core pathways affected by differential metabolites between JP and lpr groups (a). GEO database was used to determine the differential expression of pathway-related proteins in lupus patients (b). 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Investigating the Mechanisms of Jieduquyuziyin Prescription Improves Lupus Nephritis and Fibrosis via FXR in MRL/lpr Mice 