Research Article
(–)-Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
Figure 3
Gene expression responses following acute EPI treatment. HUVECs were treated with 0, 5, and 10 μM EPI over 48 h and lysed for analysis of gene expression. (a) DRP1, (b) MFN2, (c) NRF2, and (d) SOD2. Data are from 3 independent experiments. Statistical significance was determined by a two-way ANOVA, with dose and time as factors. Multiple comparisons were performed by Dunnett’s test to determine differences in gene expression between conditions.Main effect of dose; main effect of time (); , .
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