Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial
Table 3
Lipid profiles, inflammatory markers, and other parameters of the subjects within each group at different times and between groups.
Parameters
RP jelly drink ()
value within group
Placebo jelly drink ()
value within group
value between group
Baseline (CV%)
4 weeks (CV%)
8 weeks (CV%)
Baseline (CV%)
4 weeks (CV%)
8 weeks (CV%)
BMI, kg/m2
(17.62)
(19.82)
(15.69)
0.895
(18.02)
(17.15)
(17.49)
0.832
0.950
SBP, mmHg
(9.89)
(15.11)
(27.97)
0.543
(2.92)
(21.25)
(14.27)
0.230
0.945
DBP, mmHg
(2.81)
(19.53)
(19.89)
0.818
(2.77)
(11.00)
(15.79)
0.234
0.464
FPG, mg/dL
(17.35)
(22.52)
(14.11)
0.094
(3.46)
(15.05)
(21.17)
0.506
0.357
TC, mg/dL
(18.67)
(17.94)
(14.05)
0.727
(17.57)
(18.23)
(21.56)
0.214
0.530
TG, mg/dL
(56.76)
(37.88)
a (36.28)
0.020
(22.57)
a (25.37)
(33.53)
0.775
0.016
HDL-C, mg/dL
(30.64)
a (18.55)
(20.51)
0.014
(21.37)
(22.15)
(21.99)
0.447
0.780
LDL-C, mg/dL
(25.49)
aa (19.42)
aa (21.35)
0.0.29
(25.06)
(23.61)
(26.98)
0.766
0.018
MDA, nmol/mL
(6.20)
a (2.41)
(5.10)
0.001
(8.02)
(3.13)
(3.80)
0.493
0.032
GSH, μg/mL
(15.16)
a (13.77)
a (14.52)
0.091
(12.48)
(7.91)
(12.38)
0.518
0.020
TNF-α, pg/mL
(13.36)
(15.16)
a (5.61)
0.025
(15.94)
(13.67)
(10.28)
0.586
0.026
IL-6, pg/mL
(9.80)
(18.29)
(8.57)
0.810
(6.32)
(12.50)
a (15.70)
0.003
0.096
IL-10, pg/mL
(17.08)
(13.77)
(14.71)
0.516
(13.67)
(26.57)
(13.40)
0.638
0.854
MCPL-1, pg/mL
(9.91)
(4.46)
(10.08)
0.193
(4.61)
(2.97)
(9.41)
0.585
0.673
Data expressed as and the coefficient of variation percent (CV%). Data were analyzed using repeated-measured ANOVA for comparing the changes over time within and between study groups. a indicates the significant differences within each group at different times when compared to baseline ( value <0.05). BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; MDA: malondialdehyde; GSH: glutathione reduced; IL: interleukin; TNF-α: tumor necrosis factor alpha; MCP-1: monocyte chemoattractant protein-1.
