Research Article
BHF177 Suppresses Diabetic Neuropathic Pain by Blocking PKC/CaMKII/ERK1/2/CREB Signaling Pathway through Activating GABAB Receptor
Figure 2
BHF177 increases the number of neurons positive for the GABAB receptor in DNP rats. (a) The number of cells positive for the GABAB receptor in DNP rats determined using immunohistochemistry (×200). (b) Statistic analysis of (a). vs. normal rats, # vs. DNP rats, and & vs. DNP rats treated with BHF177. animals per group.
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