Prognostic Signature Development on the Basis of Macrophage Phagocytosis-Mediated Oxidative Phosphorylation in Bladder Cancer

Figure 4

Identification and modeling of prognosis-associated macrophage phagocytosis regulators: (a) The result of PCA analysis demonstrating the efficacy of differentiating tumor from normal tissue. (b) Four phagocytic modulators screened out by COX univariate regression analysis with predictive value for the prognosis of tumor patients. (c, d) LASSO regression analysis modeling. (e) Demonstration of the predictive value of signature for 5-year survival in tumor patients. (f) Demonstration of the high value of signature in predicting 5-year survival. (f–h) Demonstration of the high-risk groups and the low-risk groups divided by (based on) 5-year survival, scores, and numbers of each group as well as the expression levels of survival time, survival events, and genes in relation to the grouping. (i) Demonstration of the high value of signature in predicting 5-year survival. (j) Columnar line graphs for the prediction of 1-year, 3-year, and 5-year overall survival in patients with bladder cancer.

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