Cysteine Donor-Based Brain-Targeting Prodrug: Opportunities and Challenges

Figure 1

The biosynthesis of glutathione. Glu: glutamate; Cys: cysteine; γ-GCS: γ-glutamylcysteine synthetase; ATP: adenosine triphosphate; Gly: glycine; GS: glutathione synthetase; GSH: glutathione.