Bioactive Compounds and Their Derivatives: An Insight into Prospective Phytotherapeutic Approach against Alzheimer’s Disease

Figure 2

Amyloid cascade in Alzheimer’s disease (AD). ER: endoplasmic reticulum; Aβ: amyloid-beta; NFT: neurofibrillary tangle; APP: amyloid precursor protein, ROS: reactive oxygen species; NO: nitric oxide; TNF-α: tumor necrosis factor-alpha [38].