Research Article

The Imbalance of Mitochondrial Homeostasis of Peripheral Blood-Derived Macrophages Mediated by MAFLD May Impair the Walking Ability of Elderly Patients with Osteopenia

Table 1

Baseline characteristics and clinical features.

OPeOPe with MAFLDSO-value

Gender12/2212/253/330.016
Age0.070
BMI0.648
Smoke26/432/529/70.724
Alcohol25/532/530/60.914
Hypertension18/1122/1526/100.490
Diabetes28/131/630/60.207
Exercise (yes or no)9/1723/1118/130.035
MNA0.116
PSQI0.733
Calf girth0.293
Waist line0.991
FTSST
Six-minute walking0.755
SPPB
Grip0.034
Ca0.309
P0.542
P1NP/CROSSL
CROSSL0.146
PTH0.338
VITAMIN D0.036
OSTEOC0.360
P1NP
Lumbar BMD0.889
Neck BMD<0.001
Total BMD0.711
ALT0.096
AST0.023
TC0.824
TG
LDL0.849
HDL0.209
BUN0.840
Scr0.010
SUA0.324
eGFR0.037
Lumbar-t value-1.05 ± 1.24-2.51 ± 1.280.564
Neck of femur-t value0.064
Total-t value0.153

Abbreviations: OPe: osteopenia; OPe with MAFLD: osteopenia combined with MAFLD; SO: severe osteoporosis; BMI: body mass index; FTSST: five times sit to stand test; PSQI: Pittsburgh Sleep Quality Index; MNA-SF: Mini Nutritional Assessment-Short Form; SPPB: Short Physical Performance Battery; BMD: bone mineral density; eGFR: Estimated Glomerular Filtration Rate; TG: triglycerides; TC: total cholesterol; Scr: serum creatinine; SUA: serum uric acid; BUN: blood urea nitrogen; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ALT: alanine aminotransferase; AST: aspartate transaminase; P: blood phosphorus; Ca: blood calcium; P1NP: N-Propeptide of Type I Procollagen; CROSSL: β-Crosslaps; PTH: parathyroid hormone; OSTEOC: osteocalcin. The value in red means that the value and is considered to be significantly important.