Research Article
Attenuation of the Severity of Acute Respiratory Distress Syndrome by Pomiferin through Blocking Inflammation and Oxidative Stress in an AKT/Foxo1 Pathway-Dependent Manner
Figure 2
Pomiferin treatment significantly improved pulmonary function and acid-base equilibrium in mice with ARDS. (a–c) Mice were injected with LPS (5 mg/kg) intratracheally treated with or without pomiferin (20 mg/kg/day) intragastrically. Noninvasive pulmonary functional parameters including total volume, ventilation, and lung compliance were detected (). (d, e) Arterial blood gas analysis of PaO2, PaCO2, and HCO3- (). vs. control group, # vs. ARDS group.
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