DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis

Figure 4

The expression levels of FOXP3 after down-regulation of DNMT3b in ox-LDL cultures of isolated Tregs. . (a) The mRNA expression levels of DNMT3b by stimulating with AZA and EGCG. (b) The mRNA expression levels of DNMT3b by transduced with DNMT3b shRNA. (c) The mRNA expression levels of FOXP3 by stimulating with AZA and EGCG. (d) The mRNA expression levels of FOXP3 by transduced with DNMT3b shRNA. (e) Western blot results of DNMT3b and FXOP3 after down-regulation of DNMT3b. (f) The protein expression levels of DNMT3b by stimulating with AZA and EGCG. (g) The protein expression levels of DNMT3b by transduced with DNMT3b shRNA. (h) The protein expression levels of FOXP3 by stimulating with AZA and EGCG. (i) The protein expression levels of FOXP3 by transduced with DNMT3b shRNA. Abbreviations: AZA: 5-aza-2-deoxycytidine; DNMT3b: DNA methyltransferases 3b; EGCG: epigallocatechin-3-gallate; FOXP3: forkhead box P3; ox-LDL: oxidized low-density lipoprotein.

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