DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis

Figure 5

Cytokine level in ox-LDL cultures of isolated Tregs. , . (a) The concentrations of TGF-β by stimulating with AZA and EGCG in ox-LDL cultures of isolated Tregs. (b) The concentrations of TGF-β by transduced with DNMT3b shRNA in ox-LDL cultures of isolated Tregs. (c) The concentrations of IL-10 by stimulating with AZA and EGCG in ox-LDL cultures of isolated Tregs. (d) The concentrations of IL-10 by transduced with DNMT3b shRNA in ox-LDL cultures of isolated Tregs. (e) The concentrations of IFN-γ by stimulating with AZA and EGCG in ox-LDL cultures of isolated Tregs. (f) The concentrations of IFN-γ by transduced with DNMT3b shRNA in ox-LDL cultures of isolated Tregs. (g) The concentrations of IL-1β by stimulating with AZA and EGCG in ox-LDL cultures of isolated Tregs. (h) The concentrations of IL-1β by transduced with DNMT3b shRNA in ox-LDL cultures of isolated Tregs. Abbreviations: AZA: 5-aza-2-deoxycytidine; DNMT3b: DNA methyltransferases 3b; EGCG: epigallocatechin-3-gallate; FOXP3: forkhead box P3; ox-LDL: oxidized low-density lipoprotein.

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