Insulin-Related Liver Pathways and the Therapeutic Effects of Aerobic Training, Green Coffee, and Chlorogenic Acid Supplementation in Prediabetic Mice

Figure 3

HFP promotes PD in mice. (a) Ctrl and HFD mice, (b and c) the percentage changes of bodyweight (12 weeks), and weight gain ([the final body weight (23 weeks) - the primary bodyweight (12 weeks)]). (d-g) Plasma Biochemical Analysis including (d and e) fasting blood glucose (FBG) concentration, glucose tolerance test (GTT), and the area under the curve (AUC) in Ctrl and HFD groups. (f) Plasma insulin concentration and (g) HOMA index in Ctrl and HFD groups. (h) Immunoblot analyses of liver lysates for protein level evaluations such as p-AKT and total AKT in Ctrl and HFD groups. All values are presented as . and indicate significant statistical differences in HFD compared to Ctrl mice.

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