Research Article

Insulin-Related Liver Pathways and the Therapeutic Effects of Aerobic Training, Green Coffee, and Chlorogenic Acid Supplementation in Prediabetic Mice

Figure 4

HFD promotes liver damage in mice. (a) Liver morphology of Ctrl and HFD mice. (b) The percentage change of liver weight (The ratio of liver to total body weight for Ctrl and HFD mice). (c) Histopathology of liver sections (PAS staining) from Ctrl and HFD mice (arrows indicate glycogen accumulations). (d) Quantitative assessment of hepatic glycogen (mg/g). (e) Systematic plasma levels of specific liver enzymes (AST and ALT ) in Ctrl and HFD mice. All values are presented as . , and indicate significant statistical differences in HFD compared to Ctrl mice.
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