Insulin-Related Liver Pathways and the Therapeutic Effects of Aerobic Training, Green Coffee, and Chlorogenic Acid Supplementation in Prediabetic Mice

Figure 6

Several treatments mitigated HDF-associated metabolic changes. (a) Weight of mice in the PD, GC, CGA, EX, EX. GC, and EX.CGA groups. (b) The final weight of mice in the PD, GC, CGA, EX, EX. GC, and EX.CGA groups compared to weights at week 12. (c) Measurement of fasting blood glucose (FBG), (d) glucose tolerance test (GTT), and the area under the curve (AUC) in PD and all treated groups at the end of the 22^nd week. (e) Measurement of plasma insulin concentration and (f) HOMA index in PD and all treated groups at the end of the 22^nd week. (g) Immunoblot analysis of protein levels of p-AKT and total AKT in livers from PD and all treated group mice. All values are presented as . , , and indicate significant statistical differences in the treated compared to PD mice.

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