Research Article

Orcinol Glucoside Improves Senile Osteoporosis through Attenuating Oxidative Stress and Autophagy of Osteoclast via Activating Nrf2/Keap1 and mTOR Signaling Pathway

Figure 5

OG upregulates Nrf2/Keap1 pathway in bone tissue of SAMP6 mice and osteoclast derived from RAW264.7 cells. (a, b) Representative Western blot analysis and the quantification of Nrf2 and Keap1 expression in bone tissue of mice and osteoclast; (c) immunofluorescence analysis for nucleus translocation of Nrf2. Scale bars: 10 μm. Each point represents (). , vs. the indicated group.
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