Inhibition of Heat Shock Protein 90 Attenuates the Damage of Blood-Brain Barrier Integrity in Traumatic Brain Injury Mouse Model

Figure 2

17-DA alleviated brain edema and damage of BBB and TJ proteins after TBI 3 days. (a, b) Representative T2-weighted images and quantified brain lesion levels were shown in different groups; the high signal on the injured side represented the edema area. (c, d) EB extravasations and quantified EB contents are shown. The blue color areas indicated extravasation of EB. (e, f) ZO-1 and occludin expressions in western blotting and quantified bar graph in different groups. Data were presented as the ( per group). .

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