Renal and Inflammatory Proteins as Biomarkers of Diabetic Kidney Disease and Lupus Nephritis

Table 2

Area under the curve.

(a)

Control vs. DKD
Biomarker	AUC	STD. error	95% C.I.	value
ASC	0.7666	0.05595	0.6570 to 0.8763	0.0002
IL-18	0.6849	0.06612	0.5553 to 0.8145	0.0069
CRP	0.6254	0.07273	0.4829 to 0.7680	0.1011
uPA	0.7522	0.07668	0.6019 to 0.9025	0.0047
EGF	0.9935	0.00877	0.9763 to 1.000	<0.0001
Lipocalin-2/NGAL	0.9554	0.03177	0.8931 to 1.000	<0.0001

(b)

Control vs. LN
Biomarker	AUC	STD. error	95% C.I.	value
ASC	0.6526	0.06274	0.5296 to 0.7756	0.0245
IL-18	0.7384	0.05906	0.6226 to 0.8541	0.0004
CRP	0.6844	0.07027	0.5466 to 0.8221	0.0097
uPA	0.7443	0.07279	0.6017 to 0.8870	0.0037
EGF	1.000	0.000	1.000 to 1.000	<0.0001
Lipocalin-2/NGAL	0.9412	0.3714	0.8684 to 1.000	<0.0001

(c)

DKD vs. LN
Biomarker	AUC	STD. error	95% C.I.	value
ASC	0.6373	0.07508	0.4901 to 0.7844	0.0684
IL-18	0.5222	0.07501	0.3752 to 0.6692	0.7623
CRP	0.5997	0.07994	0.4430 to 0.7564	0.2205
uPA	0.5980	0.09194	0.4178 to 0.7782	0.2630
EGF	0.5856	0.08860	0.4120 to 0.7593	0.3470
Lipocalin-2/NGAL	0.5546	0.1057	0.3474 to 0.7618	0.6058