[Retracted] Rhodiola Rosea Extract Counteracts Stress in an Adaptogenic Response Curve Manner via Elimination of ROS and Induction of Neurite Outgrowth

Figure 4

BDNF mRNA and mature BDNF protein levels in SH-Y5Y cells. (a) The effect of 5 ng/m RRE peaked after 3 h of treatment with a significant increase in the BDNF mRNA expression. Data are normalized to 1 (corresponding control condition) and presented as of three independent experiments. (b) Treatment with RRE at 5 ng/ml had as well an upregulating effect on the protein level of mature BDNF exhibiting a significant increase at 4 h. Data are normalized to 1 (corresponding control condition) and presented as of three independent experiments. Values represent the of three independent experiments. For statistics, unpaired Student t test versus the corresponding untreated (CTRL) of each time point was used, , , , and .

(a)

(b)