Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy

<div>CAT alleviates oxidative stress in random skin flaps. (a) Immunohistochemical staining of proteins SOD1 in random skin flaps (200 magnification; scan bar 25 <i>μ</i>m). (b) Quantification of integral absorbance of SOD1 in IHC. (c) Western blotting result of SOD1, eNOS, and HO1 in the control and CAT group. (d–f) Quantification of SOD1, eNOS, and HO1 expressions in each group. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy 