Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy

<div>CAT inhibits apoptosis in random skin flaps. (a) Immunohistochemical staining of proteins CASP3 in random skin flaps (200 magnification; scan bar, 25 <i>μ</i>m). (b) Quantification of integral absorbance of CASP3 protein. (c) Western blotting result of Bax, Bcl-2, and C-CASP3 in the control and CAT group. (d–f) Quantification of Bax, Bcl-2, and C-CASP3 expressions in each group. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Catalpol Enhances Random-Pattern Skin Flap Survival by Activating SIRT1-Mediated Enhancement of Autophagy 