Metabolomic Identification of Serum Exosome-Derived Biomarkers for Bipolar Disorder

Figure 4

Dysregulated serum exosomal metabolite coexpression modules in patients with BD. (a) Dendrogram showing metabolite coexpression modules defined in 72 samples (32 BD patients and 40 HC subjects). (b) Pearson’s correlation coefficient between gender, age, disease status, disease severity, and module eigengene. (c, d) Coexpression hub node (metabolite) network plots for blue and turquoise modules. (e) KEGG enrichment pathways for the 20 hub nodes (metabolites) in blue and turquoise modules.

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