Research Article

tRNA-Derived Fragment tRF-5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR

Figure 3

Bioinformatic analysis of tRF-5009A. (a) Barplot showing Gene Ontology (GO) enrichment for biological processes with top 10 scores. (b) Barplot showing significant GO terms as enrichment score values of significantly enriched pathways with top 10 scores for biological processes, cellular components, and molecular functions. (c) Dotplot showing gene ratios in the pathways with top 10 scores. The size of the dot indicates the number of genes with biological process terms, while the color represents the value. (d) Barplot showing significantly enriched pathways with top 10 scores. (e) GO-directed acyclic graph explanation. When a gene is annotated to a specific node, it is also considered annotated to the parent nodes.
(a)
(b)
(c)
(d)
(e)