tRNA-Derived Fragment tRF-5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR

Table 1

Baseline characteristics of patients with knee osteoarthritis ().

Characteristics	Number of cases (%)
Age (years)
<65	11 (36.7)
≥65	19 (63.3)
Gender
Male	6 (20.0)
Female	24 (80.0)
Obesity gradation^a
Underweight	0 (0.0)
Normal weight	9 (30.0)
Overweight	12 (40.0)
Obesity	9 (30.0)
Affected side
Left	16 (53.3)
Right	14 (46.7)
Disease duration (years)
<10	18 (60.0)
≥10	12 (40.0)
Kellgren-Lawrence gradation
III	13 (43.3)
IV	17 (56.7)
Expression of tRF-5009A^b
Low expression	17 (43.3)
High expression	13 (56.7)
Expression of mTOR^c
Low expression	12 (40.0)
High expression	18 (60.0)

^aUnderweight: ; normal weight: ; overweight: ; obesity: . ^bThe maximal difference (eighteenth minus seventeenth is 0.0115 in ascending order) near median was used to classify between the low expression or high expression of tRF-5009A instead of the median (sixteenth minus fifteenth is 0.0002 in ascending order). ^cThe maximal difference (thirteenth minus twelfth is 0.0833 in ascending order) near median was used to classify between the low expression or high expression of mTOR instead of the median (sixteenth minus fifteenth is 0.0149 in ascending order).