Research Article
tRNA-Derived Fragment tRF-5009A Regulates Autophagy and Degeneration of Cartilage in Osteoarthritis via Targeting mTOR
Table 2
Correlation between tRF-5009A expression and the baseline characteristics of patients with knee osteoarthritis (
).
| Characteristics | tRF-5009A expression | value | Low | High |
| Age (years) | | | | <65 | 5 | 6 | 0.454 | ≥65 | 12 | 7 | Gender | | | | Male | 3 | 3 | 1.000 | Female | 14 | 10 | Obesity gradation | | | | Underweight | 0 | 0 | 0.414 | Normal weight | 4 | 5 | | Overweight | 6 | 6 | | Obesity | 7 | 2 | | Affected side | | | | Left | 8 | 8 | 0.431 | Right | 9 | 5 | | Disease duration (years) | | | | <10 | 10 | 8 | 0.880 | ≥10 | 7 | 5 | | Kellgren-Lawrence gradation | | | | III | 2 | 11 | <0.001 | IV | 15 | 2 | |
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values were analyzed using the chi-squared test with as significant. |