An Emerging Role of Proanthocyanidins on Psoriasis: Evidence from a Psoriasis-Like Mouse Model

Figure 3

Histopathological changes of each group mice’s back skin by HE staining (×100). (a) Normal group, (b) model group, (c) low-dose PC group, (d) medium-dose PC group, (e) high-dose PC group, and (f) control group. In (b) and (f), black arrows indicate that the epidermis became thick with parakeratosis/hyperkeratosis, granular layer deficiency, spinous layer hypertrophy, telangiectasia, and perivascular inflammatory cell infiltration in the dermis. In (c), (d), and (e), the above pathological changes were improved compared with (b) and (f), especially in (e).

(a)

(b)

(c)

(d)

(e)

(f)