Research Article

Magnesium Hydride Ameliorates Endotoxin-Induced Acute Respiratory Distress Syndrome by Inhibiting Inflammation, Oxidative Stress, and Cell Apoptosis

Figure 6

MgH2 suppresses AKT/mTOR pathway and NF-κB/NLRP3/IL-1β pathway in vitro and in vivo. (a) and (b) MgH2 inhibits AKT/mTOR pathway and NF-κB/NLRP3/IL-1β pathway related proteins in vitro; NAC is used as a positive control. (c) and (d) MgH2 inhibits AKT/mTOR pathway and NF-κB/NLRP3/IL-1β pathway related proteins in vivo. (e) NLRP3 and IL-1β immunohistochemistry staining in lung tissues (100x).
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