Resveratrol Treats UVB-Induced Photoaging by Anti-MMP Expression, through Anti-Inflammatory, Antioxidant, and Antiapoptotic Properties, and Treats Photoaging by Upregulating VEGF-B Expression

Figure 2

Effect of RES on the skin of UVB-induced photoaging ICR mice. (a) Effect of RES on skin surface morphology in UVB-induced photoaging ICR mice (). (b)–(f) The depth of skin wrinkles in ICR mice measured weekly from week 3 onwards (). (g) Histopathological changes in the skin of each group of ICR mice (, ). (h) Content of collagen fibers in the skin of each group of ICR mice (, ). (i) Collagen III content in the skin of ICR mice in each group (, ). , compared with the control group; #, ##, ###, compared with the model group. C: control group; U: model group; R: RES drug-administered group.

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