Resveratrol Treats UVB-Induced Photoaging by Anti-MMP Expression, through Anti-Inflammatory, Antioxidant, and Antiapoptotic Properties, and Treats Photoaging by Upregulating VEGF-B Expression

Figure 3

Effect of RES on apoptosis in UVB-induced photoaging Hacat cells and ICR mouse skin. (a) Changes in caspase3 protein levels in photoaging Hacat cells (). (b) Relative grey values of caspase3 protein in photoaging Hacat cells using GADPH as an internal reference. (c) Relative expression content of caspase9 mRNA in photoaged Hacat cells using GADPH as an internal reference (). (d) Relative expression content of mRNA of caspase3 in the skin of photoaging ICR mice using GADPH as an internal reference (). (e) Changes in caspase3 protein levels in the skin of photoaging ICR mice (). (f) Relative grey values of caspase3 protein in the skin of photoaging ICR mice using GADPH as an internal reference. (g) Relative expression content of mRNA of caspase9 in the skin of photoaging ICR mice using GADPH as an internal reference (). , , compared to the control group; ##, ###, compared to the model group. C: control group; U: model group; R20, R40: RES concentration of 20 and 40 μM drug-administered groups.

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