Resveratrol Treats UVB-Induced Photoaging by Anti-MMP Expression, through Anti-Inflammatory, Antioxidant, and Antiapoptotic Properties, and Treats Photoaging by Upregulating VEGF-B Expression

Figure 4

Effect of RES on the gene expression of MMPs in UVB-induced photoaging Hacat cells and ICR mouse skin. (a) Relative expression content of MMP-1mRNA in photoaged Hacat cells using GADPH as an internal reference (). (b) Relative expression content of MMP-9mRNA in photoaging Hacat cells with GADPH as an internal reference (). (c) Relative expression content of MMP-3mRNA in the skin of photoaged ICR mice using GADPH as an internal reference (). (d) Changes in MMP-9 protein levels in the skin of photoaged ICR mice (). (e) Relative grayscale values of MMP-9 protein in the skin of photoaged ICR mice using GADPH as an internal reference. , , compared to the control group; ##, ###, compared to the model group. C: control group; U: model group; R40: RES concentration of 40 μM drug-administered group.

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