Resveratrol Treats UVB-Induced Photoaging by Anti-MMP Expression, through Anti-Inflammatory, Antioxidant, and Antiapoptotic Properties, and Treats Photoaging by Upregulating VEGF-B Expression

Table 28

Effect of transfected siRNA on the expression of mRNA for GPX-4, caspase3, and IL-6 in Hacat cells ().

	NC	NC + U	V	V + U	V + R20 + U
GPX-4	1.00	0.88^&	0.88^&	0.90	0.96
Caspase3	0.99	1.30^&&&	1.06	1.17	1.17
IL-6	1.00	2.52^&&&	0.98	2.36^a	2.01^b

&, &&&, compared to the NC group; ^a, compared to the V group; ^b, compared to the V + U group. NC group: transfected siRNA NC, also negative transfection control group; NC + U group: transfected siRNA NC followed by UVB irradiation; V group: transfected siRNA VEGF-B; V + U group: transfected siRNA VEGF-B followed by UVB irradiation; V + R20 + U group: transfected siRNA VEGF-B followed by 20 μM RES drug-administration, 4 hours post-UVB irradiation.