Research Article

Tongnao Decoction (TND) Alleviated Atherosclerosis by Playing Lowering Lipid, Anti-Inflammatory, and Antioxidant Roles

Figure 1

Tongnao decoction (TND) mitigated the progression of atherosclerosis in ApoE-deficient mice. The ApoE-/- mice were given a gavage of TND at a dose of 1 mg/kg per day (TND) or normal saline (AS) for 12 weeks after right carotid artery partial ligation. (a) Cross-sections of the left and right common carotid arteries were identified with the Oil Red O staining. The lesion area (b) and necrotic core size (c) of right carotid artery were quantified as the based on Oil Red O staining. ; vs. sham; ## vs. AS.
(a)
(b)
(c)