Identification of 20(S)-Ginsenoside Rh2 as a Potential EGFR Tyrosine Kinase Inhibitor

Figure 6

The result of molecular docking. (a) Docked 20(S)-Rh2 (cyan sticks) and cocrystallized ligand erlotinib (magenta sticks) in the binding pocket of EGFR (green cartoon). (b) Amino acid residues (magenta lines) of EGFR that lie within 4 Å away from 20(S)-Rh2 (cyan sticks). The hydrogen bonds were shown as black dotted lines.

(a)

(b)