Colchicine Ameliorates 5-Fluorouracil-Induced Cardiotoxicity in Rats

Table 2

Effect of COL on 5-FU-induced changes in ECG findings.

Groups	ST-elevation (mV)	QTc duration (ms)	QRS duration (ms)	RR interval (ms)	HR (bpm)
Control
5-FU	^b,c		^b,d
COL
COL+5-FU	^a,e		^b,c,f

^a,bStatistically significant differences between the control and other groups (^a, ^b). ^c,dStatistically significant differences between the COL and other groups (^c, ^d). ^kStatistically significant differences between the 5-FU and other groups (^e, ^f). Values are expressed as ; for each treatment group. HR = heart rate; bpm = beat per minute; SD =standard deviation.