Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS-Activated BV-2 Microglial Cells

Figure 3

Effects of DEAC, CM, and AMB on inflammatory cytokine release in LPS-stimulated BV-2 cells. Cells were pretreated with DEAC (100 μg/mL), CM (50 and 100 μg/mL), and AMB (25 μg/mL) for 1 h and activated with LPS (0.5 μg/mL) for additional 24 h. The results are expressed as . For statistical analysis, one-way ANOVA was used followed by the Bonferroni posttest. ^# vs. negative control (0.1% DMSO, drug vehicle); , , vs. LPS group, /group.

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