Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS-Activated BV-2 Microglial Cells

Figure 6

Effects of DEAC on TLR-4, p-NF-κB, p-JNK, and p-ERK1/2 expression in LPS-stimulated BV-2 cells. Cells were pretreated with DEAC (100 μg/mL) for 1 h and incubated with LPS (0.5 μg/mL) for 1 more hour. The results are expressed as . For statistical analysis, one-way ANOVA (a), two-way ANOVA (b–d), followed by Bonferroni posttest. ^# vs. negative control (0.1% DMSO, drug vehicle), ; vs. LPS group, /group.

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