Research Article
Aβ1–40 Oligomers Trigger Neutrophil Extracellular Trap Formation through TLR4- and NADPH Oxidase-Dependent Pathways in Age-Related Macular Degeneration
Figure 3
Release of NETs from neutrophils from donors with AMD. (a and b) The release of NETs was quantified every hour from 1 h to 4 h and from 0 μM to 10 μM. (c and d) Measurements of extracellular DNA and NE levels indicated the presence of NETs. . (e) Human neutrophils were isolated from the peripheral blood of individuals with AMD and HCs and incubated at 37°C for 4 h in the absence of any stimulation. PMA was considered the positive group. (f) Immunofluorescence analysis of H3-Cit and MPO and their colocalization with extracellular DNA. . .
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