Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age-Related Erectile Dysfunction

<div>Knockdown of IGFBP3 inhibited CCSMC-related fibrosis. (a) qRT–PCR analysis of collagen I and MMP9 in CCSMCs from each group. (b, c) Western blot analysis of collagen I and MMP9 in CCSMCs from each group. (d, e) Immunofluorescence analysis of collagen I in each group. 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Oxidative Medicine and Cellular Longevity

fig8

Figure 8

Figure 8: Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age-Related Erectile Dysfunction 

Figure 8 | Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age-Related Erectile Dysfunction 