TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice

Figure 3

CAG inhibited proinflammatory cytokines and IgE without liver or kidney toxicity. (a) The expression of BALF IL-4. (b) The expression of BALF IL-5. (c) The expression of BALF IL-13. (d) The expression of BALF IL-17A. (e) The expression of serum IgE. (f) The expression of serum ALT. (g) The expression of serum AST. (h) The expression of serum TBIL. (i) The expression of serum BUN. (j) The expression of serum Cr. (k) Representative images of liver sections and kidney sections (l) via H&E staining (×200). Scale bar: 50 μm. in each group of the normal control (N) group, OVA-induced asthma model (A) group, CAG prevention (CP) group, CAG treatment (CT) group, and dexamethasone (D) group. Error bars are . , , and vs. N group; #, ##, ###, and #### vs. A group by one-way ANOVA.

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