Research Article
TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice
| Protein ID | Gene name | Description | Peptides | Asthma model (A) vs. Normal control (N) | CAG treatment (CT) vs. Asthma model (A) | value | Ratio | Regulated type | value | Ratio | Regulated type |
| P24063 | Itgal | Integrin alpha-L OS=Mus musculus OX=10090 GN=Itgal PE=1 SV=2 | 5 | 0.001 | 1.354 | Up | 0.034 | 0.808 | Down | P48025 | Syk | Tyrosine-protein kinase SYK OS=Mus musculus OX=10090 GN=Syk PE=1 SV=2 | 16 | 0.001 | 1.487 | Up | 0.041 | 0.771 | Down | P27870 | Vav1 | Proto-oncogene vav OS=Mus musculus OX=10090 GN=Vav1 PE=1 SV=1 | 13 | 0.001 | 1.430 | Up | 0.036 | 0.803 | Down |
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Italic and bold indicated upregulated or downregulated expression.
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