Research Article

TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice

Table 2

3 DEPs regulated by CAG.

Protein IDGene nameDescriptionPeptidesAsthma model (A) vs. Normal control (N)CAG treatment (CT) vs. Asthma model (A)
valueRatioRegulated type valueRatioRegulated type

P24063ItgalIntegrin alpha-L OS=Mus musculus OX=10090 GN=Itgal PE=1 SV=250.0011.354Up0.0340.808Down
P48025SykTyrosine-protein kinase SYK OS=Mus musculus OX=10090 GN=Syk PE=1 SV=2160.0011.487Up0.0410.771Down
P27870Vav1Proto-oncogene vav OS=Mus musculus OX=10090 GN=Vav1 PE=1 SV=1130.0011.430Up0.0360.803Down

Italic and bold indicated upregulated or downregulated expression.