Anxiolytic Effect of Carvedilol in Chronic Unpredictable Stress Model

Table 1

Daily stressors used in chronic unpredictable stress induction. Adapted from Kumar, Kuhad, and Chopra [38].

Day	Time/period	Stressors
1^st	5 min/morning	Swimming in cold water (12°C)
2^nd	30s/afternoon	Tail pinch
3^rd	24 h/night	Water and food deprivation
4^th	12h/night	Night lighting
5^th	—	No stress
6^th	15 min/morning	Swimming in water at room temperature ()
7^th	60s/afternoon	Tail pinch
8^th	5 min/morning	Swimming in cold water (12°C)
9^th	12h/night	Night lighting
10^th	—	No stress
11^th	10 min/morning	Swimming in water at room temperature ()
12^th	90s/afternoon	Tail pinch
13^th	5 min/morning	Swimming in cold water (12°C)
14^th	24 h/afternoon	Water and food deprivation
15^th	12h/night	Night lighting
16^th	—	No stress
17^th	24 h/morning	Water and food deprivation
18^th	60s/afternoon	Tail pinch
19^th	15 min/morning	Swimming in water at room temperature ()
20^th	12 h/night	Night lighting
21^st	5 min/morning	Swimming in cold water (12 °C)