Modulation of the p38 MAPK Pathway by Anisomycin Promotes Ferroptosis of Hepatocellular Carcinoma through Phosphorylation of H3S10

Figure 3

Anisomycin (AN) increased phosphorylation of p38 MAPK and H3S10 in HCC cells. (a) Western blotting analysis of p38 MAPK, p-p38 MAPK, H3, and p-H3S10 in HCC cells after a 24 h DMSO, AN, or AN+SB203580 (SB) treatment. Immunofluorescence costained for p-p38 MAPK and p-H3S10 showed their expression levels and cellular localization at different time points of AN treatment in Hep3B (b) and HCCLM3 (c).

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