Research Article

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats

Table 2

Effects of MPHE, hesperidin, and quercetin on serum total bilirubin and albumin levels and LDH activity of NAPAP-administrated rats.

GroupsParameter
LDH (U/L)% changeTotal bilirubin (mg/dl)% changeAlbumin (g/dl)% change

Normal0.70 ± 0.04
NAPAP98.31a87.14a-16.09
NAPAP+MPHEb-54.77b-51.90b15.49
NAPAP+hesperidinb-51.98b-53.43b17.71
NAPAP+quercetinb-51.96b-48.85b19.18

Data are expressed as . The number of animals in each group is 6. aSignificant at in comparison with the normal values. bSignificant at in comparison with NAPAP values. Percentage changes are calculated by comparing NAPAP-administered control with normal control and NAPAP-administered treated rats with NAPAP-administered control.