Research Article

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen-Induced Hepatonephrotoxicity in Wistar Rats

Table 3

Effect of MPHE, hesperidin, and quercetin on serum urea, uric acid, and creatinine levels of NAPAP-administered rats.

GroupsParameter
Urea (mg/dl)% changeUric acid (mg/dl)% changeCreatinine (mg/l)% change

Normal
NAPAPa168.24a92.59a83.02
NAPAP+MPHEb-62.72b-55.13b-45.36
NAPAP+hesperidinb-55.93b-56.41b-47.42
NAPAP+quercetinb-59.81b-59.94b-53.61

Data are expressed as . The number of animals in each group is 6. aSignificant at in comparison with the normal values. bSignificant at in comparison with NAPAP values. Percentage changes are calculated by comparing NAPAP-administered control with normal control and NAPAP-administered treated rats with NAPAP-administered control.